Investigation of the synergistic effect of platelet-rich plasma and polychromatic light on human dermal fibroblasts seeded chitosan/gelatin scaffolds for wound healing

Highlights

Biochemical/biophysical stimulant-based 3D scaffold was developed for the treatment of chronic wounds.
Fibroblasts on the scaffold were stimulated chemically with platelet rich plasma and physically by polychromatic light.
The dual effect of light on platelets activation and stimulation of fibroblasts was demonstrated.
The 3D cell migration model showed that cell migration increased in the presence of PRP and light.

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